main character in doom3, since he just shuts the ---- up the entire game. Alyx and Tommy vercetti where cool too.
The GODDESS SAMUS From metroid (Super metroid: all time greatest game). Dante is a close second. Vincent is looking awesome in Dirge of Cerberus also.
Mine would have to be Cloud from Final Fantasy 7. Come on? How many 150 lb guys do you know that can swing a 10 ton sword? ^_^